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POLE 产品

(Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Categories

Participates in DNA repair and in chromosomal DNA replication.

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Featured POLE Categories

POLE 抗体

High quality antibodies with extensive validation data.

Recommended POLE 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7150239
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (2)
Cat. No. ABIN519022
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN2178556
Quantity 100 μL
Datasheet Datasheet

Recommended POLE 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315634
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our POLE Products

Gaspar, Mendes, Corrêa-da-Silva, Lima-Junior, Gaspar, Ropelle, Araujo, Carvalho, Velloso: "Downregulation of HIF complex in the hypothalamus exacerbates diet-induced obesity." in: Brain, behavior, and immunity, Vol. 73, pp. 550-561, (2018) (PubMed).

Asahara, Li, Fuss, Haines, Vlatkovic, Boyd, Linn: "Stimulation of human DNA polymerase epsilon by MDM2." in: Nucleic acids research, Vol. 31, Issue 9, pp. 2451-9, (2003) (PubMed).

Li, Pursell, Linn: "Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon." in: The Journal of biological chemistry, Vol. 275, Issue 30, pp. 23247-52, (2000) (PubMed).

Vlatkovic, Guerrera, Li, Linn, Haines, Boyd: "MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon." in: Nucleic acids research, Vol. 28, Issue 18, pp. 3581-6, (2000) (PubMed).

Liu, Linn: "Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis." in: Nucleic acids research, Vol. 28, Issue 21, pp. 4180-8, (2000) (PubMed).

Li, Asahara, Patel, Zhou, Linn: "Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32337-44, (1998) (PubMed).

Islas, Fairley, Morgan: "DNA synthesis on discontinuous templates by human DNA polymerases: implications for non-homologous DNA recombination." in: Nucleic acids research, Vol. 26, Issue 16, pp. 3729-38, (1998) (PubMed).

Kramata, Downey, Paborsky: "Incorporation and excision of 9-(2-phosphonylmethoxyethyl)guanine (PMEG) by DNA polymerase delta and epsilon in vitro." in: The Journal of biological chemistry, Vol. 273, Issue 34, pp. 21966-71, (1998) (PubMed).

Chui, Linn: "Further characterization of HeLa DNA polymerase epsilon." in: The Journal of biological chemistry, Vol. 270, Issue 14, pp. 7799-808, (1995) (PubMed).

Synonyms and alternative names related to POLE

DNA polymerase epsilon, catalytic subunit (POLE), polymerase (DNA directed), epsilon (Pole), DNA polymerase epsilon, catalytic subunit (Pole), DNA polymerase epsilon 2, accessory subunit (POLE2), polymerase (DNA directed), epsilon 2 (p59 subunit) (Pole2), CRCS12, DPE2, FILS, POLE1

Protein level used designations for POLE

  • DNA polymerase II subunit A
  • DNA polymerase epsilon catalytic subunit A
  • DNA-directed DNA polymerase epsilon
  • pol-epsilon
  • DNA polymerase II subunit 2
  • DNA polymerase epsilon subunit 2
  • DNA polymerase epsilon subunit B
  • polymerase (DNA directed), epsilon 2 (p59 subunit)
  • DNA polymerase epsilon small subunit
  • DNA polymerase epsilon, subunit 2
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