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POLG 抗体

(Polymerase (DNA Directed), gamma (POLG))
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
POLG 抗体  (C-Term) POLG 抗体  (C-Term) POLG 抗体 (C-Term) (ABIN2854742)

POLG 适用: 人 WB, IHC (p), IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

POLG 抗体  (AA 1101-1239) POLG 抗体  (AA 1101-1239) POLG 抗体 (AA 1101-1239) (ABIN1714946)

POLG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

POLG 抗体  (AA 1041-1239) POLG 抗体  (AA 1041-1239) POLG 抗体 (AA 1041-1239) (ABIN7441298)

POLG 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

POLG 抗体 by 适用

Find POLG 抗体 for a variety of species such as anti-Human POLG, anti-Mouse POLG, anti-Rat POLG. The species listed below are among those available. Click on a link to go to the corresponding products.

POLG 抗体 by 应用范围

Find POLG 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

POLG 抗体 by 抗体来源

Find POLG 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

POLG 抗体 by 抗原表位

Find POLG 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

POLG 抗体 by 克隆形成能力

Find available monoclonal or polyclonal POLG 抗体. Click on a link to go to the corresponding products.

POLG 抗体 by 克隆

Find POLG 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

POLG 抗体 by 标记

Find POLG 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular POLG 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC, IP
Validations
  • (5)
Cat. No. ABIN2854742
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN1714946
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN7441298
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN1681071
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), IF, FACS
Validations
  • (3)
Cat. No. ABIN5534169
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
  • (1)
Cat. No. ABIN1696002
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7150263
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Cow, Hamster, Human, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6747379
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2783430
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1701444
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1699630
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1708836
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1710647
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1712461
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1694176
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our POLG 抗体

Chen, Zhao, Cai, Sun, Hu, Huang, Kong, Kong: "The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways." in: Redox biology, Vol. 12, pp. 987-1003, (2017) (PubMed).

Prasad, Çağlayan, Dai, Nadalutti, Zhao, Gassman, Janoshazi, Stefanick, Horton, Krasich, Longley, Copeland, Griffith, Wilson: "DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria." in: DNA repair, Vol. 60, pp. 77-88, (2017) (PubMed).

Li, Guo, Ying, Chen, Yang, Chen, Long, Qin, Pei, Liu: "Valproic acid-induced hepatotoxicity in Alpers syndrome is associated with mitochondrial permeability transition pore opening-dependent apoptotic sensitivity in an induced pluripotent stem cell model." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 5, pp. 1730-9, (2015) (PubMed).

Mancini, Roncaglia, Brussino, Stevanin, Lo Buono, Krmac, Maltecca, Gazzano, Bartoletti Stella, Calvaruso, Iommarini, Cagnoli, Forlani, Le Ber, Durr, Brice, Ghigo, Casari, Porcelli, Funaro, Gasparre et al.: "Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways. ..." in: BMC medical genomics, Vol. 6, pp. 22, (2013) (PubMed).

Roos, Macao, Fusté, Lindberg, Jemt, Holme, Moslemi, Oldfors, Falkenberg: "Subnormal levels of POLγA cause inefficient initiation of light-strand DNA synthesis and lead to mitochondrial DNA deletions and progressive external ophthalmoplegia [corrected]." in: Human molecular genetics, Vol. 22, Issue 12, pp. 2411-22, (2013) (PubMed).

Wu, Li, Zhang, Wu, Huang, Chen: "Mitochondrial DNA base excision repair and mitochondrial DNA mutation in human hepatic HuH-7 cells exposed to stavudine." in: Mutation research, Vol. 664, Issue 1-2, pp. 28-38, (2009) (PubMed).

Aliases for POLG 抗体

polymerase (DNA) gamma, catalytic subunit L homeolog (polg.L) 抗体
DNA polymerase gamma, catalytic subunit (Polg) 抗体
DNA polymerase gamma, catalytic subunit (POLG) 抗体
polymerase (DNA directed), gamma (POLG) 抗体
polymerase (DNA directed), gamma (polg) 抗体
polymerase (DNA directed), gamma (Polg) 抗体
AA409516 抗体
MDP1 抗体
MIRAS 抗体
MTDPS4A 抗体
MTDPS4B 抗体
PEO 抗体
POLG 抗体
POLG1 抗体
POLGA 抗体
PolgA 抗体
SANDO 抗体
SCAE 抗体
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