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Phospholipase C gamma 2 抗体

(Phospholipase C gamma 2 (PLCG2))
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011].

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  • 抗原: Phospholipase C gamma 2 (PLCG2)
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7842905
Phospholipase C gamma 2 抗体 PLCG2 · Primary Antibody 人 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 200 μL
发货至: 中国
ABIN5514741
Phospholipase C gamma 2 抗体 (Middle Region) PLCG2 · Primary Antibody 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
  • 25 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
产品编号 ABIN7842905
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗原表位
Middle Region
产品编号 ABIN5514741
100 μL (More quantities available)
发货至: 中国
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Latest Publications for our Phospholipase C gamma 2 抗体

Diaz-Flores, Goldschmidt, Depeille, Ng, Akutagawa, Krisman, Crone, Burgess, Williams, Houseman, Shokat, Sampath, Bollag, Roose, Braun, Shannon: "PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras." in: Science signaling, Vol. 6, Issue 304, pp. ra105, (2013) (PubMed).

Holodick, Tumang, Rothstein: "Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells." in: Molecular immunology, Vol. 46, Issue 15, pp. 3029-36, (2009) (PubMed).

Kim, Sekiya, Poulin, Bae, Rhee: "Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 9986-99, (2004) (PubMed).

Suzuki-Inoue, Wilde, Andrews, Auger, Siraganian, Sekiya, Rhee, Watson: "Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 1023-9, (2004) (PubMed).

Humphries, Dangelmaier, Sommer, Kipp, Kato, Griffith, Bakman, Turk, Daniel, Rawlings: "Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker." in: The Journal of biological chemistry, Vol. 279, Issue 36, pp. 37651-61, (2004) (PubMed).

Watanabe, Hashimoto, Ishiai, Matsushita, Baba, Kishimoto, Kurosaki, Tsukada: "Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling." in: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 38595-601, (2001) (PubMed).

Yue, Ku, Liu, Simon, Sanborn: "Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C." in: The Journal of biological chemistry, Vol. 275, Issue 39, pp. 30220-5, (2000) (PubMed).

Ohta, Matsui, Nazawa, Kagawa: "Complete cDNA encoding a putative phospholipase C from transformed human lymphocytes." in: FEBS letters, Vol. 242, Issue 1, pp. 31-5, (1989) (PubMed).

Aliases for Phospholipase C gamma 2 抗体

phospholipase C, gamma 2 (Plcg2) 抗体
phospholipase C gamma 2 (PLCG2) 抗体
phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2) 抗体
phospholipase C gamma 2 (Plcg2) 抗体
APLAID 抗体
FCAS3 抗体
Plcg-2 抗体
PLCgamma2 抗体
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