Phospholipase C gamma 2 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for Phospholipase C gamma 2 抗体 (Middle Region) (ABIN5514741)
抗原
See all Phospholipase C gamma 2 (PLCG2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- PLCG2 Antibody - middle region
-
序列
- ETHLRCAEFE LRLTDPVPNP NPHESKPWYY DSLSRGEAED MLMRIPRDGA
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against PLCG2. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human PLCG2
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72780-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- Phospholipase C gamma 2 (PLCG2)
-
别名
- PLCG2
-
背景
-
Background Information: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.
Alternative Symbols: FCAS3, APLAID, PLC-IV, PLC-gamma-2
-
分子量
- 139kDa
-
基因ID
- 5336
-
NCBI登录号
- NP_002652
-
UniProt
- P16885
-
途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
抗原
-