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Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (Middle Region) Peptide

ZFP36 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN986434
发货至: 中国
  • 抗原 See all ZFP36 products
    ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-ZFP36 antibody (Catalog #: ARP38304_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
    别名
    G0S24 Peptide, GOS24 Peptide, NUP475 Peptide, RNF162A Peptide, TIS11 Peptide, TTP Peptide, zfp-36 Peptide, c3h-1 Peptide, g0s24 Peptide, gos24 Peptide, nup475 Peptide, rnf162a Peptide, tis11 Peptide, ttp Peptide, ZFP36 Peptide, C3H-1 Peptide, Gos24 Peptide, Nup475 Peptide, TIS11D Peptide, TISII Peptide, Tis11 Peptide, Ttp Peptide, Zfp-36 Peptide, ZFP36 ring finger protein Peptide, ZFP36 ring finger protein L homeolog Peptide, tristetraproline Peptide, Tristetraproline Peptide, similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth Peptide, zinc finger protein 36 Peptide, ZFP36 Peptide, zfp36.L Peptide, EDI_287240 Peptide, Bm1_42085 Peptide, LOAG_03119 Peptide, zfp36 Peptide, Zfp36 Peptide
    背景
    ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.

    Alias Symbols: G0S24, GOS24, NUP475, RNF162A, TIS11, TTP

    Protein Interaction Partner: PTGS2,tax,CCDC85B,EDC3,EXOSC6,EXOSC8,HMGB1,MAPKAPK2,NUP214,SFN,UPF2,XRN1,YWHAB,YWHAG,YWHAH,CCDC85B,NUP214,YWHAB,YWHAH

    Protein Size: 326
    分子量
    34 kDa
    基因ID
    7538
    NCBI登录号
    NM_003407, NP_003398
    UniProt
    P26651
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