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YY1 Associated Factor 2 (YAF2) (Middle Region) Peptide

YAF2 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN986279
发货至: 中国
  • 抗原 See all YAF2 products
    YAF2 (YY1 Associated Factor 2 (YAF2))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-YAF2 antibody (Catalog #: ARP32676_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    YAF2 (YY1 Associated Factor 2 (YAF2))
    别名
    MGC75686 Peptide, YAF2 Peptide, zgc:136577 Peptide, si:ch211-155a11.5 Peptide, 2810021M11Rik Peptide, YY1 associated factor 2 Peptide, YY1-associated factor 2 Peptide, yaf2 Peptide, YAF2 Peptide, LOC100221270 Peptide, Yaf2 Peptide
    背景
    YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.

    Alias Symbols: MGC41856

    Protein Interaction Partner: GABPB1,MYCN,YY1,CBX3,YY1

    Protein Size: 180
    分子量
    20 kDa
    基因ID
    10138
    NCBI登录号
    NM_005748, NP_005739
    UniProt
    Q8IY57
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