UPF2 Regulator of Nonsense Transcripts 2 (UPF2) (N-Term) Peptide
UPF2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all RENT2/UPF2 (UPF2) products
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- KAPEDKKKRL EDDKRKKEDK ERKKKDEEKV KAEEESKKKE EEEKKKHQEE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-UPF2 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
- 别名
- HUPF2 Peptide, RENT2 Peptide, smg-3 Peptide, UPF2, regulator of nonsense mediated mRNA decay Peptide, UPF2 regulator of nonsense transcripts homolog (yeast) Peptide, UPF2 Peptide, Upf2 Peptide, upf2 Peptide
- 背景
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This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.
Alias Symbols: DKFZp434D222, HUPF2, KIAA1408, MGC138834, MGC138835, RENT2, smg-3
Protein Interaction Partner: UPF1,DCP1B,DCP2,EIF1,EIF4A1,EIF4G1,EXOSC1,EXOSC10,EXOSC4,EXOSC6,EXOSC8,LSM1,MAP1A,MAP1LC3B,NOB1,PHB2,RPL5,RPS15,RPS25,SKIV2L2,SMG1,UPF1,UPF2,UPF3B,XRN1,XRN2,ZFP36,ZNF408,DCP2,EIF4A1,EXOSC10,EXOSC2,EXOSC4,LSM1,MAP1A,PARN,POLD1,RPS15,RPS25,SMG1,UPF1,UPF2,UP
Protein Size: 1272 - 分子量
- 148 kDa
- 基因ID
- 26019
- NCBI登录号
- NM_015542, NP_056357
- UniProt
- Q9HAU5
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