TNFRSF1A-Associated Via Death Domain (TRADD) (Middle Region) Peptide
TRADD
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all TRADD products
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TRADD antibody (Catalog #: AVARP02012_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
- 别名
- TRADD Peptide, Hs.89862 Peptide, 9130005N23Rik Peptide, AA930854 Peptide, wu:fc59e02 Peptide, zgc:103556 Peptide, tradd Peptide, TNFRSF1A associated via death domain Peptide, conjugal transfer protein D Peptide, TNFRSF1A-associated via death domain Peptide, TNFRSF1A-associated via death domain L homeolog Peptide, tnfrsf1a-associated via death domain Peptide, TRADD Peptide, traDd Peptide, Tradd Peptide, tradd.L Peptide, tradd Peptide
- 背景
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TRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Hs.89862, MGC11078
Protein Interaction Partner: FADD,FADD,KRT14,KRT18,NGFR,TNFRSF1A,TNFRSF1A,TRAF2,BCL10,BIRC3,CEP110,DAPK1,FADD,FAS,HIPK2,KRT14,KRT18,NGFR,PPP2R1A,RIPK1,STAT1,TNFRSF10A,TNFRSF10B,TNFRSF1A,TNFRSF21,TNFRSF25,TRADD,TRAF1,TRAF2,TRAF3,TRPC4AP,BCL10,CASP8,CAV1,FADD,FADD,HIPK2,KRT18,NGFR,NOL3,RIPK1,STAT1,TNF,TNFRSF10A,TNFRSF10B,TNFRSF1A,TNFRSF1A,TNFRSF21,TNFRSF25,TRADD,TRAF1,TRAF2,TRAF2,TRPC4AP
Protein Size: 312 - 分子量
- 34 kDa
- 基因ID
- 8717
- NCBI登录号
- NM_003789, NP_003780
- UniProt
- Q15628
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