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Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) (Middle Region) Peptide

TFPI 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN985011
发货至: 中国
  • 抗原 See all TFPI products
    TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    QEKPDFCFLE EDPGICRGYI TRYFYNNQTK QCERFKYGGC LGNMNNFETL
    产品特性
    This is a synthetic peptide designed for use in combination with anti-TFPI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
    别名
    EPI Peptide, LACI Peptide, TFI Peptide, TFPI1 Peptide, A630013F22Rik Peptide, AW552122 Peptide, TFPI Peptide, si:dz44f8.1 Peptide, tfpib Peptide, wu:fb92g01 Peptide, zgc:152844 Peptide, zgc:158592 Peptide, tissue factor pathway inhibitor Peptide, tissue factor pathway inhibitor a Peptide, TFPI Peptide, Tfpi Peptide, tfpia Peptide
    背景
    This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.

    Alias Symbols: EPI, LACI, TFI, TFPI1

    Protein Interaction Partner: ELANE,F10,MMP1,MMP12,MMP7,MMP8,MMP9,PRSS3,THBS1,F10,PRSS3,THBS1

    Protein Size: 304
    分子量
    33 kDa
    基因ID
    7035
    NCBI登录号
    NM_006287, NP_006278
    UniProt
    P10646
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