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Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (Middle Region) Peptide

TERF2IP 适用: 小鼠 宿主: 合成 BP, WB
产品编号 ABIN984958
发货至: 中国
  • 抗原 See all RAP1 (TERF2IP) products
    RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
    蛋白结构域
    Middle Region
    宿主
    小鼠
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    LTYVKENARS PSSVTGNALW KAMEKSSLTQ HSWQSLKDRY LKHLRGQEHK
    产品特性
    This is a synthetic peptide designed for use in combination with anti-Terf2ip Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
    别名
    DRIP5 Peptide, RAP1 Peptide, Rap1 Peptide, cRAP1 Peptide, TERF2 interacting protein Peptide, telomeric repeat binding factor 2, interacting protein Peptide, TERF2IP Peptide, Terf2ip Peptide
    背景
    Terf2ip acts both as a regulator of telomere function and as a transcription regulator. It is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.

    Alias Symbols: Rap1

    Protein Size: 286
    分子量
    31 kDa
    基因ID
    57321
    NCBI登录号
    NM_020584, NP_065609
    UniProt
    Q91VL8
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