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Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (N-Term) Peptide

TCF7L1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN984907
发货至: 中国
  • 抗原 See all TCF7L1 products
    TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
    蛋白结构域
    N-Term
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-TCF7L1 antibody (Catalog #: ARP57917_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
    别名
    TCF-3 Peptide, TCF3 Peptide, Tcf-3 Peptide, Tcf3 Peptide, bHLHb21 Peptide, tcf3c Peptide, tcf3d Peptide, xtcf3 Peptide, XTCF-3 Peptide, tcf7l1 Peptide, tcf3b Peptide, TCF-3-A Peptide, tcf-3 Peptide, tcf3 Peptide, tcf3a Peptide, zTcf-3 Peptide, transcription factor 7 like 1 Peptide, transcription factor 7 like 1 (T cell specific, HMG box) Peptide, transcription factor 7 like 1 L homeolog Peptide, transcription factor 7 like 1 S homeolog Peptide, transcription factor 7 like 1b Peptide, transcription factor 7 like 1a Peptide, TCF7L1 Peptide, Tcf7l1 Peptide, tcf7l1.L Peptide, tcf7l1.S Peptide, tcf7l1b Peptide, tcf7l1a Peptide
    背景
    TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.

    Alias Symbols: TCF-3, TCF3

    Protein Interaction Partner: CTNNB1,CTNNB1

    Protein Size: 588
    分子量
    63 kDa
    基因ID
    83439
    NCBI登录号
    NM_031283, NP_112573
    UniProt
    Q9HCS4
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