TANK-Binding Kinase 1 (TBK1) Peptide
TBK1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all TBK1 products
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TBK1 antibody (Catalog #: ARP54921_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- 别名
- nak Peptide, t2k Peptide, TBK1 Peptide, wu:fk70c05 Peptide, zgc:136548 Peptide, NAK Peptide, T2K Peptide, 1200008B05Rik Peptide, AI462036 Peptide, AW048562 Peptide, TANK binding kinase 1 L homeolog Peptide, TANK binding kinase 1 Peptide, TANK-binding kinase 1 Peptide, tbk1.L Peptide, TBK1 Peptide, tbk1 Peptide, Tbk1 Peptide
- 背景
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The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ11330, NAK, T2K
Protein Interaction Partner: TICAM1,AZI2,CDC37,HSP90AA1,HSP90AB1,IKBKB,IKBKG,IRF3,IRF5,MAVS,NCK1,NFKBIA,RELA,SIKE1,TANK,TBK1,TICAM1,TRAF2,ANKRD28,BTRC,CDC37,CUL1,CYLD,HSP90AA2,IKBKG,IRF3,NCK1,NFKB1,NFKB2,PPP6C,PPP6R1,PPP6R2,REL,RELA,SKP1,TANK,TBKBP1,TNFAIP3,TRAF2,TRAF3,UBC
Protein Size: 729 - 分子量
- 84 kDa
- 基因ID
- 29110
- NCBI登录号
- NM_013254, NP_037386
- UniProt
- Q9UHD2
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