Synovial Sarcoma, X Breakpoint 4B (SSX4B) (Middle Region) Peptide
SSX4B
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all SSX4B products
- SSX4B (Synovial Sarcoma, X Breakpoint 4B (SSX4B))
- 蛋白结构域
- Middle Region
- 宿主
- 人
- 资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- MRSKRAADFH GNDFGNDRNH RNQVERPQMT FGSLQRIFPK IMPKKPAEEE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SSX4B Antibody(ARP50423_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SSX4B (Synovial Sarcoma, X Breakpoint 4B (SSX4B))
- 别名
- CT5.4 Peptide, SSX family member 4B Peptide, SSX4B Peptide
- 背景
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The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: SSX4, CT5.4
Protein Interaction Partner: HIF1A
Protein Size: 188 - 分子量
- 22 kDa
- 基因ID
- 548313
- NCBI登录号
- NM_001034832, NP_001030004
- UniProt
- O60224
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