This is a synthetic peptide designed for use in combination with anti-SMG5 antibody (Catalog #: ARP55229_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
SMG5 plays a role in nonsense-mediated mRNA decay. SMG5 does not have RNase activity by itself. SMG5 promotes dephosphorylation of RENT1. SMG5 is necessary for TERT activity.SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM].
Alias Symbols: EST1B, FLJ34864, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5
Protein Interaction Partner: SMG7,SMG1,SMG6,SMG7,TERT,UPF1,TERT