Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) (N-Term) Peptide
SLC7A5
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all SLC7A5 products
- SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- MAGAGPKRRA LAAPAAEEKE EAREKMLAAK SADGSAPAGE GEGVTLQRNI
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SLC7A5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) peptide
SLC7A5 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
- 别名
- 4F2LC Peptide, CD98 Peptide, D16S469E Peptide, E16 Peptide, LAT1 Peptide, MPE16 Peptide, hLAT1 Peptide, D0H16S474E Peptide, TA1 Peptide, JHI-21 Peptide, SLC7A5 Peptide, LAT-1 Peptide, slc7a5a Peptide, 4F2 Peptide, 4F2HC Peptide, AI314110 Peptide, Cd98 Peptide, Ly-10 Peptide, Ly-m10 Peptide, Ly10 Peptide, Mdu1 Peptide, Mgp-2hc Peptide, NACAE Peptide, solute carrier family 7 member 5 Peptide, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 Peptide, solute carrier family 7 (amino acid transporter light chain, L system), member 5 Peptide, solute carrier family 7 member 5 S homeolog Peptide, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Peptide, SLC7A5 Peptide, Slc7a5 Peptide, slc7a5.S Peptide, Slc3a2 Peptide
- 背景
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SLC7A5 is a sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. SLC7A5 is involved in cellular amino acid uptake. SLC7A5 acts as an amino acid exchanger. SLC7A5 is involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. SLC7A5 plays a role in neuronal cell proliferation (neurogenesis) in brain. SLC7A5 is involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. SLC7A5 is involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. SLC7A5 may play an important role in high-grade gliomas. SLC7A5 mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. SLC7A5 acts as the major transporter of tyrosine in fibroblasts.
Alias Symbols: 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1
Protein Interaction Partner: SLC3A2,SLC3A2,UBC
Protein Size: 507 - 分子量
- 56 kDa
- 基因ID
- 8140
- NCBI登录号
- NM_003486, NP_003477
- UniProt
- Q01650
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