Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (Middle Region) Peptide
SKA1
适用: 人, 小鼠
宿主: 合成
BP, WB
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- 抗原 See all SKA1 products
- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
- 蛋白结构域
- Middle Region
- 宿主
- 人, 小鼠
- 资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- LLNKFELEIQ YQEQTNSSLK ELCESLREEC EDVEHLKEHV PPHLPQVTAT
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Ska1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
- 别名
- C18H18orf24 Peptide, C18orf24 Peptide, 2810433K01Rik Peptide, AV117428 Peptide, RGD1310784 Peptide, spindle and kinetochore associated complex subunit 1 Peptide, SKA1 Peptide, ska1 Peptide, Ska1 Peptide
- 背景
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Ska1 is a Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. It is required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.
Alias Symbols: 2810433K01Rik, AV117428
Protein Size: 254 - 分子量
- 28 kDa
- 基因ID
- 66468
- NCBI登录号
- NM_025581, NP_079857
- UniProt
- Q9CPV1
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