SIN3B
(SIN3 Transcription Regulator Homolog B (SIN3B))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-SIN3B antibody (Catalog #: ARP50589_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
SIN3B
(SIN3 Transcription Regulator Homolog B (SIN3B))
别名
fj63d08 Peptide, si:dkey-6n6.6 Peptide, wu:fj63d08 Peptide, 2810430C10Rik Peptide, SIN3 transcription regulator family member B Peptide, SIN3 transcription regulator family member B S homeolog Peptide, transcriptional regulator, SIN3B (yeast) Peptide, sin3b Peptide, SIN3B Peptide, sin3b.S Peptide, Sin3b Peptide
背景
SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.
Alias Symbols: KIAA0700
Protein Interaction Partner: HDAC1,HDAC9,IKZF1,IKZF4,MAD1L1,MXD1,MXI1,REST,SETDB1,ZBTB16,HCFC1,HDAC1,HDAC9,IKZF1,IKZF2,IKZF3,IKZF4,MECP2,RNF220,SAP30,SETDB1,SUDS3,WHSC1,ZBTB16