SART3
(Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
蛋白结构域
Middle Region
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-SART3 antibody (Catalog #: ARP34329_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing. The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KIAA0156, MGC138188, RP11-13G14, TIP110, p110(nrb), P100, p110, DSAP1
Protein Interaction Partner: AR,COIL,MEGF10,PRPF3,RNPS1,AR,C3orf17,C3orf26,CDK9,DDX47,FRG1,LSM2,LSM4,LSM6,LSM7,MEPCE,MLF1IP,NAA38,PPIH,PRPF3,PRPF31,PRPF4,RNPS1,RPF2,RRP15,SNRPB,SRBD1,TUT1,USP15,USP39,USP4