Glutaminyl-Peptide Cyclotransferase (QPCT) (Middle Region) Peptide
QPCT
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all QPCT products
- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-QPCT antibody (Catalog #: ARP48743_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
- 别名
- GCT Peptide, QC Peptide, sQC Peptide, QPCT Peptide, 5730422A13Rik Peptide, Qpctl1 Peptide, RGD1562284 Peptide, qpct Peptide, glutaminyl-peptide cyclotransferase Peptide, glutaminyl-peptide cyclotransferase (glutaminyl cyclase) Peptide, glutaminyl-peptide cyclotransferase L homeolog Peptide, QPCT Peptide, Qpct Peptide, M6_Spy0443 Peptide, M5005_Spy_0416 Peptide, M28_Spy0404 Peptide, CJA_2408 Peptide, CCNA_02733 Peptide, Tsp_03182 Peptide, qpct.L Peptide
- 背景
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QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GCT, QC, sQC
Protein Size: 361 - 分子量
- 38 kDa
- 基因ID
- 25797
- NCBI登录号
- NM_012413, NP_036545
- UniProt
- Q16769
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