This is a synthetic peptide designed for use in combination with anti-PTPRN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
PTPRN
(Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
别名
IA-2 Peptide, IA-2/PTP Peptide, IA2 Peptide, ICA512 Peptide, R-PTP-N Peptide, mIA-A Peptide, mKIAA4064 Peptide, Ia-2 Peptide, fc43c04 Peptide, ptprn Peptide, wu:fc43c04 Peptide, ia-2 Peptide, ia2 Peptide, ica512 Peptide, r-ptp-n Peptide, protein tyrosine phosphatase, receptor type N Peptide, protein tyrosine phosphatase, receptor type, N Peptide, protein tyrosine phosphatase, receptor type, Na Peptide, protein tyrosine phosphatase, receptor type N L homeolog Peptide, PTPRN Peptide, Ptprn Peptide, ptprna Peptide, ptprn.L Peptide
背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Alias Symbols: IA2, IA-2, ICA512, R-PTP-N, IA-2/PTP