This is a synthetic peptide designed for use in combination with anti-PTPN11 Antibody(ARP56494_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
PTPN11
(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
别名
BPTP3 Peptide, CFC Peptide, NS1 Peptide, PTP-1D Peptide, PTP2C Peptide, SH-PTP2 Peptide, SH-PTP3 Peptide, SHP2 Peptide, 2700084A17Rik Peptide, AW536184 Peptide, PTP1D Peptide, SAP-2 Peptide, SHP-2 Peptide, Shp2 Peptide, Syp Peptide, SYP Peptide, bptp3 Peptide, cfc Peptide, ns1 Peptide, ptp-2 Peptide, ptp2c Peptide, ptpn11 Peptide, ptpn11-a Peptide, ptpn11-b Peptide, shp-2 Peptide, shp2 Peptide, fa14b09 Peptide, wu:fa14b09 Peptide, wu:fi24f03 Peptide, zgc:55388 Peptide, zgc:63553 Peptide, protein tyrosine phosphatase, non-receptor type 11 Peptide, protein tyrosine phosphatase, non-receptor type 11 S homeolog Peptide, protein tyrosine phosphatase, non-receptor type 11, a Peptide, protein tyrosine phosphatase, non-receptor type 11, b Peptide, PTPN11 Peptide, Ptpn11 Peptide, ptpn11.S Peptide, ptpn11a Peptide, ptpn11b Peptide
物质类
Viral Protein
背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Protein Interaction Partner: BCR,CAT,CAV1,FLT1,GAB1,GRB2,KIT,PDGFRB,PDGFRB,SLAMF1,cagA,ACTN4,ARHGAP1,AXL,BCR,BDKRB2,BTLA,C6orf25,CAT,CAV1,CBL,CCKBR,CD33,CDH5,CEACAM1,CHUK,CRKL,CSF2RB,CSF3R,CTLA4,CXCR4,DAB1,DDR1,EGFR,EPHA2,EPOR,ERBB2,FLT1,FLT4,FRS2,FRS3,FYN,GAB1,GAB2,GAB3,GHR,GRB2,GRI