PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Peptide
PTK2B
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all PTK2B products
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PTK2B antibody (Catalog #: ARP32685_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- 别名
- CADTK Peptide, CAKB Peptide, FADK2 Peptide, FAK2 Peptide, PKB Peptide, PTK Peptide, PYK2 Peptide, RAFTK Peptide, CAKbeta Peptide, E430023O05Rik Peptide, Raftk Peptide, Pyk2 Peptide, fak1b Peptide, ptk2.2 Peptide, ptk2b Peptide, si:ch1073-355e8.1 Peptide, protein tyrosine kinase 2 beta Peptide, PTK2 protein tyrosine kinase 2 beta Peptide, protein tyrosine kinase 2aa Peptide, PTK2B Peptide, Ptk2b Peptide, ptk2aa Peptide
- 背景
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PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.
Alias Symbols: PKB, PTK, CAKB, FAK2, PYK2, CADTK, FADK2, RAFTK
Protein Interaction Partner: SORBS2,ARHGAP21,ARHGAP5,ASAP1,ASAP2,BCAR1,CBL,CCR5,CRK,DLG3,DLG4,DLGAP3,EFS,EGFR,ERBB2,ERBB3,EWSR1,FGFR2,FGFR3,FLT1,FYN,GNA13,GRB2,GRIN2A,GSN,IL7R,ITGB2,ITGB3,JAK1,JAK2,JAK3,KCNA2,LCK,LPXN,LYN,MAP3K4,MATK,MCAM,MYH2,NEDD9,NPHP1,PDCD6IP,PDPK1,PIK3R1,PITPNM1,PITPNM2,PITPNM3,PRKCD,PTK2,PTK2B,PTK2B,PTPN11,PTPN12,PTPN6,PXN,RASA1,RB1CC1,SH2D3C,SHC1,SLC2A1,SNCA,SORBS2,SRC,STAP1,STAT3,SYK,TGFB1I1,TLN1,VAV1,ZAP70,ASAP2,BCAR1,CBL,CD2AP,DCC,DLG3,DLG4,EGFR,ERBB2,EWSR1,FYN,GIT1,GNA13,GRB2,GRIN2A,GSN,IL7R,ITGB2,ITGB3,JAK1,JAK2,JAK3,KCNA2,LCK,LPXN,LYN,NEDD9,NPHP1,PITPNM1,PITPNM2,PITPNM3,PRKCD,PTK2B,PTPN11,PTPN12,PTPN6,PXN,RASA1,RB1CC1,SLC2A1,SOCS3,SORBS1,SORBS2,SRC,SYK,TGFB1I1,TLN1,VAV1
Protein Size: 1009 - 分子量
- 116 kDa
- 基因ID
- 2185
- NCBI登录号
- NM_004103, NP_004094
- UniProt
- Q14289
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