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Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) (Middle Region) Peptide

PTGIS 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN982431
发货至: 中国
  • 抗原 See all PTGIS products
    PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PTGIS antibody (Catalog #: ARP44377_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
    别名
    CYP8 Peptide, CYP8A1 Peptide, PGIS Peptide, PTGI Peptide, Cyp8 Peptide, Cyp8a1 Peptide, Pgis Peptide, ptgisl Peptide, PTGIS Peptide, prostaglandin I2 synthase Peptide, prostaglandin I2 (prostacyclin) synthase Peptide, prostacyclin synthase Peptide, PTGIS Peptide, Ptgis Peptide, ptgis Peptide, VDBG_06319 Peptide
    背景
    PTGIS is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CYP8, CYP8A1, MGC126858, MGC126860, PGIS, PTGI

    Protein Size: 500
    分子量
    57 kDa
    基因ID
    5740
    NCBI登录号
    NM_000961, NP_000952
    UniProt
    Q16647
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