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PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1) Peptide

PPFIBP1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN982058
发货至: 中国
  • 抗原 See all PPFIBP1 products
    PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PPFIBP1 antibody (Catalog #: ARP42133_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
    别名
    liprin-beta-1 Peptide, L2 Peptide, SGT2 Peptide, hSGT2 Peptide, hSgt2p Peptide, 4632409B19Rik Peptide, AW214454 Peptide, AW261454 Peptide, PPFIA binding protein 1 Peptide, PTPRF interacting protein, binding protein 1 (liprin beta 1) Peptide, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog Peptide, Ppfibp1 Peptide, ppfibp1 Peptide, ppfibp1.S Peptide, PPFIBP1 Peptide
    背景
    PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Alias Symbols: L2, hSGT2, hSgt2p, SGT2

    Protein Interaction Partner: PPFIA1,PPFIA2,PPFIA3,PPFIBP1,PTPRM,S100A4,YWHAG,PPFIA1,PPFIA2,PPFIBP1,S100A4,SFN,YWHAG,YWHAQ

    Protein Size: 170
    分子量
    19 kDa
    基因ID
    8496
    NCBI登录号
    NM_177444, NP_803193
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