POU Class 1 Homeobox 1 (POU1F1) Peptide
POU1F1
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all POU1F1 products
- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-POU1F1 antibody (Catalog #: ARP31419_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
- 别名
- CPHD1 Peptide, GHF-1 Peptide, PIT1 Peptide, POU1F1a Peptide, Pit-1 Peptide, Hmp1 Peptide, Pit1 Peptide, Pit1-rs1 Peptide, dw Peptide, dwarf Peptide, GHF1 Peptide, GHF1A Peptide, PIT1Z Peptide, PIT-1 Peptide, Pit-1* Peptide, pit1 Peptide, pit-1 Peptide, POU class 1 homeobox 1 Peptide, POU domain, class 1, transcription factor 1 Peptide, POU1F1 Peptide, Pou1f1 Peptide, pou1f1 Peptide
- 背景
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PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
Alias Symbols: PIT1, CPHD1, GHF-1, Pit-1, POU1F1a
Protein Interaction Partner: CREBBP,ETS1,GATA2,JUN,NR1I2,NR1I3,NR3C1,PITX1,GATA2,JUN,NR1I2,NR1I3,NR3C1,PITX1,PPARA,PPARG,VDR
Protein Size: 291 - 分子量
- 33 kDa
- 基因ID
- 5449
- NCBI登录号
- NM_000306, NP_000297
- UniProt
- P28069
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