Protocadherin alpha 4 (PCDHA4) Peptide
PCDHA4
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all PCDHA4 products
- PCDHA4 (Protocadherin alpha 4 (PCDHA4))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PCDHA4 antibody (Catalog #: ARP46960_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PCDHA4 (Protocadherin alpha 4 (PCDHA4))
- 别名
- CNR1 Peptide, CNRN1 Peptide, CRNR1 Peptide, PCDH-ALPHA4 Peptide, Cnr1 Peptide, Crnr1 Peptide, R75250 Peptide, PCDHA4 Peptide, CNRv4 Peptide, Pcdha4 Peptide, protocadherin alpha 4 Peptide, protocadherin alpha-4 Peptide, PCDHA4 Peptide, Pcdha4 Peptide, LOC100713594 Peptide, LOC100629843 Peptide
- 背景
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The gene encoding PCDHA4 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: CNR1, CNRN1, CRNR1, MGC138307, MGC142169, PCDH-ALPHA4
Protein Interaction Partner: APLP1,C14orf1,C1orf103,C7orf64,CCDC90B,EEF1A1,GAPDH,GDF9,IGSF21,RELN,SETDB1,TLE1,TP53,UNC119,APLP1,C14orf1,C1orf103,C7orf64,CCDC90B,EEF1A1,GAPDH,GDF9,IGSF21,SETDB1,TLE1,TP53,UNC119
Protein Size: 947 - 分子量
- 99 kDa
- 基因ID
- 56144
- NCBI登录号
- NM_018907, NP_061730
- UniProt
- Q9UN74
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