This is a synthetic peptide designed for use in combination with anti-PACS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Alias Symbols: -
Protein Interaction Partner: CLCN7,PKD2,TRPV4,nef,CLCN7,CSNK2A1,FURIN,GGA3,IGF2R,JUN,PKD2,PPP2CA,PPP2CB,VAMP4,CSNK2A1,FGFR1OP,FURIN,GGA3,VAMP4