Numb Homolog (NUMB) (C-Term) Peptide
NUMB
适用: 人, 小鼠
宿主: 合成
BP, WB, IHC
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- 抗原 See all NUMB products
- NUMB (Numb Homolog (NUMB))
- 蛋白结构域
- C-Term
- 宿主
- 人, 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ASGNRHAEVP PGTCPVDPFE AQWAALESKS KQRTNPSPTN PFSSDLQKTF
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Numb Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Numb Homolog (NUMB) peptide
NUMB 适用: 人, 小鼠, Cow, 犬 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- NUMB (Numb Homolog (NUMB))
- 别名
- C14orf41 Peptide, S171 Peptide, c14_5527 Peptide, Nb Peptide, NUMB, endocytic adaptor protein Peptide, numb homolog (Drosophila) Peptide, NUMB Peptide, Numb Peptide, numb Peptide
- 背景
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Numb plays a role in the process of neurogenesis. It is required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. It is not required for the proliferation of neural progenitor cells before the onset of neurogenesis. It is also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. It may also mediate local repair of brain ventricular wall damage.
Alias Symbols: m-numb, mnb, m-Nb
Protein Interaction Partner: Lnx2,Lnx1,Ehd1,Ehd4,Lnx1,Eps15
Protein Size: 604 - 分子量
- 66 kDa
- 基因ID
- 18222
- NCBI登录号
- NM_010949, NP_035079
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