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Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) Peptide

NR2C1 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN980900
发货至: 中国
  • 抗原 See all NR2C1 products
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-NR2C1 antibody (Catalog #: ARP38287_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    别名
    TR2 Peptide, NR2C1 Peptide, dor2 Peptide, tr2-11 Peptide, xDOR2 Peptide, DKFZp468M0512 Peptide, si:dkey-183c16.2 Peptide, zgc:110672 Peptide, 4831444H07Rik Peptide, 80.3 Peptide, Eenr Peptide, Tr2-11 Peptide, Tr2 Peptide, Psg4 Peptide, TR2-11 Peptide, PSG9 Peptide, nr2c1 Peptide, nuclear receptor subfamily 2 group C member 1 Peptide, nuclear receptor subfamily 2 group C member 1 S homeolog Peptide, nuclear receptor subfamily 2, group C, member 1 Peptide, pregnancy specific beta-1-glycoprotein 4 Peptide, nuclear receptor subfamily 2 group C member 1 L homeolog Peptide, NR2C1 Peptide, nr2c1.S Peptide, nr2c1 Peptide, Nr2c1 Peptide, PSG4 Peptide, nr2c1.L Peptide
    背景
    The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites

    Alias Symbols: TR2, TR2-11

    Protein Interaction Partner: AR,ESR1,HDAC3,HDAC4,NR2C2,NRIP1,AR,ESR1,HDAC3,HDAC4

    Protein Size: 603
    分子量
    67 kDa
    基因ID
    7181
    NCBI登录号
    NM_003297, NP_003288
    UniProt
    Q15625
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