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Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4) (Middle Region) Peptide

NR1H4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN980883
发货至: 中国
  • 抗原 See all NR1H4 products
    NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    CRLRKCKEMG MLAECMYTGL LTEIQCKSKR LRKNVKQHAD QTVNEDSEGR
    产品特性
    This is a synthetic peptide designed for use in combination with anti-NR1H4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
    别名
    zgc:110190 Peptide, zgc:92742 Peptide, NR1H4 Peptide, BAR Peptide, FXR Peptide, HRR-1 Peptide, HRR1 Peptide, RIP14 Peptide, AI957360 Peptide, Fxr Peptide, Rxrip14 Peptide, nuclear receptor subfamily 1, group H, member 5 S homeolog Peptide, nuclear receptor subfamily 1, group H, member 4 Peptide, nuclear receptor subfamily 1 group H member 4 Peptide, nr1h5.S Peptide, nr1h4 Peptide, NR1H4 Peptide, Nr1h4 Peptide
    背景
    This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Alias Symbols: NR1H4,BAR, FXR, HRR1, RIP14,

    Protein Size: 486
    分子量
    54 kDa
    基因ID
    9971
    UniProt
    Q96RI1
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