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Minichromosome Maintenance Complex Component 6 (MCM6) Peptide

MCM6 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN979901
发货至: 中国
  • 抗原 See all MCM6 products
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-MCM6 antibody (Catalog #: ARP36650_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    别名
    CG4039 Peptide, DmMCM6 Peptide, DmeMCM6 Peptide, Dmel\\CG4039 Peptide, MCM6 Peptide, McM6 Peptide, fs(1)K1214 Peptide, mcm6 Peptide, MCG40308 Peptide, Mis5 Peptide, P105MCM Peptide, Mcmd6 Peptide, mis5 Peptide, mmcm6 Peptide, ASP-l1 Peptide, D1Wsu22e Peptide, Minichromosome maintenance 6 Peptide, DNA replication licensing factor MCM6 Peptide, minichromosome maintenance complex component 6 Peptide, minichromosome maintenance complex component 6 L homeolog Peptide, DNA replication licensing factor mcm-6 Peptide, Mcm6 Peptide, TP02_0113 Peptide, PVX_114735 Peptide, CMU_027970 Peptide, MCM6 Peptide, mcm6.L Peptide, mcm-6 Peptide
    背景
    The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

    Alias Symbols: MCG40308, Mis5, P105MCM

    Protein Interaction Partner: MCM2,MCM2,MCM4,MCM4,MCM6,ALS2CR11,CCNA1,CDT1,CRLS1,GMNN,IL1F5,ING5,MCM10,MCM2,MCM3,MCM4,MCM6,MCM7,MCM8,MLLT3,ORC2L,ORC6L,PSMA1,SCNM1,SMC1A,AIRE,ALS2CR11,CDC45,CDT1,IL1F5,ING5,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCM8,MLLT3,ORC1L,ORC2L,ORC4L,PMS1,PSMA1,RPA1,SCNM1,TAF10,TNFAIP3,USP49,USP7

    Protein Size: 821
    分子量
    90 kDa
    基因ID
    4175
    NCBI登录号
    NM_005915, NP_005906
    UniProt
    Q14566
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