Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (N-Term) Peptide
MASP1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all MASP1 products
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- PGSFMSITFR SDFSNEERFT GFDAHYMAVD VDECKEREDE ELSCDHYCHN
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MASP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 别名
- AW048060 Peptide, CCPII Peptide, Crarf Peptide, Masp1/3 Peptide, 3MC1 Peptide, CRARF Peptide, CRARF1 Peptide, MAP1 Peptide, MASP Peptide, MASP3 Peptide, MAp44 Peptide, PRSS5 Peptide, RaRF Peptide, mannan-binding lectin serine peptidase 1 Peptide, mannan binding lectin serine peptidase 1 Peptide, Masp1 Peptide, MASP1 Peptide
- 背景
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This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway.
Alias Symbols: CRARF, CRARF1, DKFZp686I01199, FLJ26383, MASP, MGC126283, MGC126284, PRSS5, RaRF
Protein Size: 699 - 分子量
- 28 kDa
- 基因ID
- 5648
- NCBI登录号
- NM_001879, NP_001870
- UniProt
- P48740
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