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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4) (Middle Region) Peptide

KCNJ4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN978799
发货至: 中国
  • 抗原 See all KCNJ4 products
    KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-KCNJ4 antibody (Catalog #: ARP35167_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))
    别名
    KCNJ4 Peptide, CKIR2.3 Peptide, HIR Peptide, HIRK2 Peptide, HRK1 Peptide, IRK-3 Peptide, IRK3 Peptide, Kir2.3 Peptide, Kcnf2 Peptide, MB-IRK3 Peptide, Hirk2 Peptide, potassium voltage-gated channel subfamily J member 4 Peptide, potassium inwardly-rectifying channel, subfamily J, member 4 Peptide, KCNJ4 Peptide, Kcnj4 Peptide
    背景
    KCNJ4 is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have??een found for this gene. Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neuronsSeveral different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.

    Alias Symbols: HIR, HIRK2, HRK1, IRK3, Kir2.3, MGC142066, MGC142068, IRK-3

    Protein Interaction Partner: CASK,DLG1,DLG2,DLG4,GNGT2,IL16,KCNJ2,LIN7B,PRKCD,CASK,DLG1,DLG2,DLG4,DMD,GNGT2,IL16,LIN7A,LIN7B,LIN7C,SNTA1

    Protein Size: 445
    分子量
    49 kDa
    基因ID
    3761
    NCBI登录号
    NM_004981, NP_004972
    UniProt
    P48050
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