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Interleukin 5 Receptor, alpha (IL5RA) (N-Term) Peptide

IL5RA 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN978515
发货至: 中国
  • 抗原 See all IL5RA products
    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
    蛋白结构域
    N-Term
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    GLAQVLLQWK PNPDQEQRNV NLEYQVKINA PKEDDYETRI TESKCVTILH
    产品特性
    This is a synthetic peptide designed for use in combination with anti-IL5RA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
    别名
    MGC86517 Peptide, IL5RA Peptide, il5r Peptide, cdw125 Peptide, hsil5r3 Peptide, gpIL-5ra Peptide, CD125 Peptide, CDw125 Peptide, HSIL5R3 Peptide, IL5R Peptide, Il5r Peptide, interleukin 5 receptor subunit alpha L homeolog Peptide, interleukin 5 receptor subunit alpha Peptide, interleukin 5 receptor, alpha Peptide, il5ra.L Peptide, IL5RA Peptide, il5ra Peptide, Il5ra Peptide
    背景
    The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

    Alias Symbols: CD125, CDw125, HSIL5R3, IL5R, MGC26560

    Protein Size: 420
    分子量
    46 kDa
    基因ID
    3568
    NCBI登录号
    NM_175726, NP_783853
    UniProt
    Q01344
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