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Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Peptide

IGLL1 适用: 人 宿主: 合成 WB, BP
产品编号 ABIN978447
发货至: 中国
  • 抗原 See all IGLL1 products
    IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
    宿主
    资源
    • 3
    • 1
    合成
    应用范围
    Western Blotting (WB), Blocking Peptide (BP)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-IGLL1 antibody (Catalog #: ARP42547_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
    别名
    14.1 Peptide, AGM2 Peptide, CD179b Peptide, IGL1 Peptide, IGL5 Peptide, IGLJ14.1 Peptide, IGLL Peptide, IGO Peptide, IGVPB Peptide, VPREB2 Peptide, IGLV Peptide, IGLL1 Peptide, MGC151892 Peptide, Igll1 Peptide, BB139905 Peptide, Igl-5 Peptide, Igll Peptide, Lambda5 Peptide, immunoglobulin lambda like polypeptide 1 Peptide, immunoglobulin lambda-like polypeptide 1 Peptide, IGLL1 Peptide, Igll1 Peptide
    背景
    The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in its gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made.The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: 14.1, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2, AGM2

    Protein Interaction Partner: IGLL1,MYOC

    Protein Size: 213
    分子量
    19 kDa
    基因ID
    3543
    NCBI登录号
    NM_020070, NP_064455
    UniProt
    P15814
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