Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
产品特性
This is a synthetic peptide designed for use in combination with anti-HTR3A antibody (Catalog #: AVARP13046_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R