Hyaluronan Synthase 1 (HAS1) (N-Term) Peptide
HAS1
适用: 人
宿主: 合成
BP, WB
-
- 抗原 See all HAS1 products
- HAS1 (Hyaluronan Synthase 1 (HAS1))
- 蛋白结构域
- N-Term
- 宿主
- 人
- 资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- EPAAAGAVGA GAYREVEAED PGRLAVEALV RTRRCVCVAQ RWGGKREVMY
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-HAS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- HAS1 (Hyaluronan Synthase 1 (HAS1))
- 别名
- dg42 Peptide, Xhas1 Peptide, HAS Peptide, shas1 Peptide, hyaluronan synthase 1 Peptide, hyaluronan synthase 1 S homeolog Peptide, has1 Peptide, HAS1 Peptide, Has1 Peptide, has1.S Peptide
- 背景
-
Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis.
Alias Symbols: HAS
Protein Interaction Partner: EIF6,VHL
Protein Size: 578 - 分子量
- 64 kDa
- 基因ID
- 3036
- NCBI登录号
- NM_001523, NP_001514
- UniProt
- Q92839
-
You are here:
