This is a synthetic peptide designed for use in combination with anti-GTF2I antibody (Catalog #: ARP58007_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
GTF2I
(General Transcription Factor III (GTF2I))
别名
BAP135 Peptide, BTKAP1 Peptide, DIWS Peptide, GTFII-I Peptide, IB291 Peptide, SPIN Peptide, TFII-I Peptide, WBS Peptide, WBSCR6 Peptide, Gtf2ird1 Peptide, 6030441I21Rik Peptide, BAP-135 Peptide, GtfII-I Peptide, Spin Peptide, bap-135 Peptide, bap135 Peptide, btkap1 Peptide, diws Peptide, gtfii-i Peptide, ib291 Peptide, spin Peptide, tfii-i Peptide, wbs Peptide, wbscr6 Peptide, gtf2i Peptide, gtf2i.L Peptide, general transcription factor IIi Peptide, general transcription factor II I Peptide, general transcription factor IIi S homeolog Peptide, GTF2I Peptide, Gtf2i Peptide, gtf2i Peptide, gtf2i.S Peptide
背景
GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants. This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Four transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: ATF6,BTK,GTF2I,HDAC3,JAK2,MAPK3,MYC,NFKB2,PIAS2,PRKG1,PRRX1,SMAD2,SRC,SRF,STAT1,STAT3,USF1,YY1,ZBTB17,ATF6,BTK,HDAC1,HDAC2,HDAC3,HDAC3,KDM1A,MAPK3,MEPCE,MYC,NAA38,NFI1,OTUB2,PHF21A,PRKG1,PRRX1,PTP4A3,Pias2,SRF,STAT1,STAT3,STX7,SUZ12,USF1,USP7