Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (Middle Region) Peptide
GRIN2B
适用: 人
宿主: 合成
BP, IHC, WB
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- 抗原 See all GRIN2B products
- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-GRIN2B antibody (Catalog #: ARP35015_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
- 别名
- NMDAR2B Peptide, GluN2B Peptide, MRD6 Peptide, NR2B Peptide, hNR3 Peptide, nmdar2b Peptide, nr2b Peptide, AW490526 Peptide, Nmdar2b Peptide, glutamate ionotropic receptor NMDA type subunit 2B Peptide, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog Peptide, glutamate receptor, ionotropic, NMDA2B (epsilon 2) Peptide, GRIN2B Peptide, Grin2b Peptide, grin2b.L Peptide
- 背景
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GRIN2B is the NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. Sequence Note: This RefSeq was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-544 U90278.1 31-574 545-545 U88963.1 545-545 546-3677 U90278.1 576-3707 3678-5941 AC007535.3 145452-147715
Alias Symbols: MGC142178, MGC142180, NMDAR2B, NR2B, hNR3, MRD6, GluN2B
Protein Interaction Partner: MAGI3,ACTN2,AP1M1,AP2M1,AP4M1,ARHGAP32,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAMK2N1,CAPN1,DLG1,DLG2,DLG3,DLG4,EPHB2,EXOC4,FYN,GNB2L1,GRIN1,GRIN2B,GRIN3A,IL16,INADL,LIN7A,LIN7B,MAGI3,PARK2,PIK3CA,PLCG1,PRKCA,PRKCB,PRKCG,PTPN11,SRC,SYNGAP1,TANC1,ACTN2,ARHGAP32,CAMK2A,DLG1,DLG2,DLG3,DLG4,Dlgap2,ERBB2IP,EXOC3,EXOC4,EXOC7,FYN,GNB2L1,GRIN1,IL16,LIN7A,LIN7B,MIB2,PARK2,UBC
Protein Size: 1484 - 分子量
- 163 kDa
- 基因ID
- 2904
- NCBI登录号
- NM_000834, NP_000825
- UniProt
- Q13224
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