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Glycoprotein V (Platelet) (GP5) (C-Term) Peptide

GP5 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN977573
发货至: 中国
  • 抗原 See all GP5 products
    GP5 (Glycoprotein V (Platelet) (GP5))
    蛋白结构域
    C-Term
    宿主
    资源
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    PNSSEPWVWA QPVTTGKGQD HSPFWGFYFL LLAVQAMITV IIVFAMIKIG
    产品特性
    This is a synthetic peptide designed for use in combination with anti-GP5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    GP5 (Glycoprotein V (Platelet) (GP5))
    别名
    lib Peptide, GPV Peptide, PLGPV Peptide, CD42d Peptide, glycoprotein V platelet L homeolog Peptide, glycoprotein V platelet Peptide, glycoprotein 5 (platelet) Peptide, glycoprotein V (platelet) Peptide, gp5.L Peptide, GP5 Peptide, Gp5 Peptide
    背景
    Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain and a beta chain, that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome, a bleeding disorder.

    Alias Symbols: CD42d

    Protein Interaction Partner: F2,GP1BA,YWHAZ,GP1BA

    Protein Size: 560
    分子量
    62 kDa
    基因ID
    2814
    NCBI登录号
    NM_004488, NP_004479
    UniProt
    P40197
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