Fucose-1-Phosphate Guanylyltransferase (FPGT) (C-Term) Peptide
FPGT
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all FPGT products
- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- SLKMNRCLKY ATMAFGVQDN LKKSVKTLSD IKLLQFFGVC FLSCLDVWNL
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-FPGT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
- 别名
- DDBDRAFT_0186414 Peptide, DDBDRAFT_0233144 Peptide, DDB_0186414 Peptide, DDB_0233144 Peptide, FPGT Peptide, DKFZp459M111 Peptide, fpgt Peptide, zgc:110694 Peptide, GFPP Peptide, 1700016E03Rik Peptide, fucose-1-phosphate guanylyltransferase Peptide, fucose-1-phosphate guanylyltransferase L homeolog Peptide, fpgt Peptide, FPGT Peptide, fpgt.L Peptide, Fpgt Peptide
- 背景
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L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.
Alias Symbols: GFPP
Protein Size: 340 - 分子量
- 37 kDa
- 基因ID
- 8790
- NCBI登录号
- NM_001199328, NP_001186257
- UniProt
- E9PNQ2
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