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Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (C-Term) Peptide

FGF8 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN976837
发货至: 中国
  • 抗原 See all FGF8 products
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    蛋白结构域
    C-Term
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    EGWYMAFTRK GRPRKGSKTR QHQREVHFMK RLPRGHHTTE QSLRFEFLNY
    产品特性
    This is a synthetic peptide designed for use in combination with anti-FGF8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    别名
    Aigf Peptide, Fgf-8 Peptide, AIGF Peptide, FGF-8 Peptide, HBGF-8 Peptide, HH6 Peptide, KAL6 Peptide, fibroblast growth factor 8 Peptide, Fgf8 Peptide, FGF8 Peptide
    背景
    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.

    Alias Symbols: AIGF, HBGF-8, KAL6, MGC149376, FGF-8

    Protein Interaction Partner: AR,FGFR1,FGFR2,FGFR3,FGFR4,FGFR3

    Protein Size: 215
    分子量
    22 kDa
    基因ID
    2253
    NCBI登录号
    NM_006119, NP_006110
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