Fibrinogen alpha Chain (FGA) Peptide
FGA
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all FGA products
- FGA (Fibrinogen alpha Chain (FGA))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-FGA antibody (Catalog #: ARP41758_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- FGA (Fibrinogen alpha Chain (FGA))
- 别名
- Fib2 Peptide, ENSMUSG00000059807 Peptide, Fib Peptide, Ac1873 Peptide, Fba5e Peptide, fibrinogen alpha chain Peptide, FGA Peptide, Fga Peptide, LOC698244 Peptide
- 背景
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FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis.The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.
Alias Symbols: Fib2
Protein Interaction Partner: BAT2,CDH5,F13A1,F2,FGA,FGB,FGG,HRG,ITGA2B,ITGB3,NID1,PLAT,SERPINA5,SERPINF2,THBS1,BAT2,CDH5,F13A1,F2,FGA,FGB,FGG,HRG,KHDRBS2,NID1,PLAT,THBS1
Protein Size: 644 - 分子量
- 71 kDa
- 基因ID
- 2243
- NCBI登录号
- NM_021871, NP_068657
- UniProt
- Q4QQH7
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