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F-Box and WD Repeat Domain Containing 8 (FBXW8) (Middle Region) Peptide

FBXW8 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN976773
发货至: 中国
  • 抗原 See all FBXW8 products
    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    RNADLDSFTT HRRHRGLIRA YEFAVDQLAF QSPLPVCRSS CDAMATHYYD
    产品特性
    This is a synthetic peptide designed for use in combination with anti-FBXW8 Antibody(ARP55586_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
    别名
    FBW6 Peptide, FBW8 Peptide, FBX29 Peptide, FBXO29 Peptide, FBXW6 Peptide, 4930438M06Rik Peptide, Fbx29 Peptide, F-box and WD repeat domain containing 8 Peptide, ring finger protein, transmembrane 2 Peptide, F-box and WD-40 domain protein 8 Peptide, FBXW8 Peptide, Fbxw8 Peptide, RNFT2 Peptide
    背景
    FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.

    Alias Symbols: FBW6, FBW8, FBX29, FBXO29, MGC33534, FBXW6

    Protein Interaction Partner: SKP1,CUL7,RBX1,SKP1,CUL7,EP300,RBX1,SKP1

    Protein Size: 598
    分子量
    67 kDa
    基因ID
    26259
    NCBI登录号
    NM_153348, NP_699179
    UniProt
    Q8N3Y1
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