F-Box Protein 31 (FBXO31) (Middle Region) Peptide
FBXO31
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all FBXO31 products
- FBXO31 (F-Box Protein 31 (FBXO31))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- QGPRESQPSP AQPRAEAPSK GPDGTPGEDG GEPGDAVAAA EQPAQCGQGQ
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-FBXO31 Antibody(ARP53775_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- FBXO31 (F-Box Protein 31 (FBXO31))
- 别名
- 1110003O08Rik Peptide, 2310046N15Rik Peptide, Fbx14 Peptide, Fbxo14 Peptide, FBX14 Peptide, FBXO14 Peptide, Fbx31 Peptide, pp2386 Peptide, RGD1561069 Peptide, fbx14 Peptide, fbx31 Peptide, fbxo14 Peptide, fbxo31 Peptide, F-box protein 31 Peptide, F-box protein 31 S homeolog Peptide, F-box protein 31 L homeolog Peptide, Fbxo31 Peptide, FBXO31 Peptide, fbxo31 Peptide, fbxo31.S Peptide, fbxo31.L Peptide
- 背景
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FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
Protein Interaction Partner: CUL1,RBX1,SKP1
Protein Size: 367 - 分子量
- 40 kDa
- 基因ID
- 79791
- NCBI登录号
- NM_024735, NP_079011
- UniProt
- Q5XUX0
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