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Ets Variant 6 (ETV6) (N-Term) Peptide

ETV6 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN976481
发货至: 中国
  • 抗原 See all ETV6 products
    ETV6 (Ets Variant 6 (ETV6))
    蛋白结构域
    N-Term
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-ETV6 antibody (Catalog #: P100806_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    ETV6 (Ets Variant 6 (ETV6))
    别名
    etv-6 Peptide, tel Peptide, tel/abl Peptide, AW123102 Peptide, AW557856 Peptide, Tel Peptide, TEL Peptide, id:ibd2308 Peptide, TEL/ABL Peptide, cmlc2 Peptide, mylc2a Peptide, zgc:92755 Peptide, ETS variant 6 Peptide, ets variant 6 Peptide, myosin, light chain 7, regulatory Peptide, etv6 Peptide, Etv6 Peptide, ETV6 Peptide, myl7 Peptide
    背景
    ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. it contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: TEL, TEL/ABL

    Protein Interaction Partner: ETV6,FLI1,HDAC9,KAT5,L3MBTL,SIN3A,SMURF1,SUMO1,UBE2I,ACTA1,CRKL,ETV6,FBXL6,FLI1,GAB2,GRB2,HDAC9,IRF8,KAT5,L3MBTL,SKP1,UBC

    Protein Size: 452
    分子量
    53 kDa
    基因ID
    2120
    NCBI登录号
    NM_001987, NP_001978
    UniProt
    P41212
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