Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2) (N-Term) Peptide
ERCC2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all ERCC2 products
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
- 蛋白结构域
- N-Term
- 宿主
- 人
- 资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-ERCC2 antibody (Catalog #: P100701_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
- 别名
- COFS2 Peptide, EM9 Peptide, TTD Peptide, XPD Peptide, AA407812 Peptide, AU020867 Peptide, AW240756 Peptide, CXPD Peptide, Ercc-2 Peptide, MGC89573 Peptide, CG9433 Peptide, DhR3 Peptide, DhXPD Peptide, DmXPD Peptide, Dmel\\CG9433 Peptide, ERCC2 Peptide, XPD/ERCC2 Peptide, l(2)SH2 2137 Peptide, l(2)SH2137 Peptide, xpd Peptide, zgc:56365 Peptide, ERCC excision repair 2, TFIIH core complex helicase subunit Peptide, excision repair cross-complementing rodent repair deficiency, complementation group 2 Peptide, excision repair cross-complementation group 2 Peptide, Xeroderma pigmentosum D Peptide, ERCC2 Peptide, Ercc2 Peptide, ercc2 Peptide, Xpd Peptide
- 背景
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The nucleotide excision repair pathway is a mechanism to repair damage to DNA. ERCC2 is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. This protein has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: COFS2, EM9, MGC102762, MGC126218, MGC126219, TTD, XPD
Protein Interaction Partner: CDK1,CDK7,ERCC2,ERCC3,ERCC5,GTF2H1,GTF2H2,RAD51,RAD52,ERCC3,ERCC5,GTF2H1,GTF2H2,HERC5,ISG15,TP53,TRIM25
Protein Size: 760 - 分子量
- 87 kDa
- 基因ID
- 2068
- NCBI登录号
- NM_000400, NP_000391
- UniProt
- P18074
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