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ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) Peptide

EDEM1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN976126
发货至: 中国
  • 抗原 See all EDEM1 products
    EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-EDEM1 antibody (Catalog #: ARP47054_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
    别名
    zgc:55816 Peptide, edem Peptide, EDEM1 Peptide, EDEM Peptide, A130059K23Rik Peptide, mKIAA0212 Peptide, RGD1563633 Peptide, ER degradation enhancer, mannosidase alpha-like 1 Peptide, ER degradation enhancing alpha-mannosidase like protein 1 Peptide, ER degradation-enhancing alpha-mannosidase-like protein 1 Peptide, ER degradation enhancing alpha-mannosidase like protein 1 L homeolog Peptide, edem1 Peptide, EDEM1 Peptide, LOC100637820 Peptide, edem1.L Peptide, Edem1 Peptide
    背景
    EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.

    Alias Symbols: EDEM, KIAA0212

    Protein Interaction Partner: CANX,BZW1,CANX

    Protein Size: 657
    分子量
    74 kDa
    基因ID
    9695
    NCBI登录号
    NM_014674, NP_055489
    UniProt
    Q92611
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