E2F Transcription Factor 1 (E2F1) (N-Term) Peptide
E2F1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all E2F1 products
- E2F1 (E2F Transcription Factor 1 (E2F1))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-E2F1 antibody (Catalog #: P100821_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- E2F1 (E2F Transcription Factor 1 (E2F1))
- 别名
- CG6376 Peptide, DRTF1/E2F Peptide, DmE2F-1 Peptide, Dmel\\CG6376 Peptide, Dp Peptide, E(Sev-CycE)3A Peptide, E(var)3-93E Peptide, E(var)3-95E Peptide, E(var)93E Peptide, E2F Peptide, E2F-1 Peptide, E2F1 Peptide, E2f1 Peptide, Evar(3)164 Peptide, dE2F Peptide, dE2F1 Peptide, dE2f Peptide, dE2f1 Peptide, de2f1 Peptide, def21 Peptide, drosE2F1 Peptide, e2f Peptide, e2f1 Peptide, l(3)07172 Peptide, l(3)j3B1 Peptide, l(3)j3C2 Peptide, l(3)rM729 Peptide, RBAP1 Peptide, RBBP3 Peptide, RBP3 Peptide, mKIAA4009 Peptide, xE2F Peptide, ATE2FB Peptide, E2F TRANSCRIPTION FACTOR-1 E2F1 Peptide, E2F transcription factor 1 Peptide, E2FB Peptide, E2FB TRANSCRIPTION FACTOR Peptide, E2F transcription factor 1 Peptide, E2F transcription factor 1 L homeolog Peptide, E2f1 Peptide, E2F1 Peptide, e2f1.L Peptide
- 背景
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The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: E2F-1, RBBP3, RBP3, RBAP1
Protein Interaction Partner: E2F2,E2F4,RBL2,BARD1,BIRC5,BRCA1,CBX5,CCDC76,CCNA1,CCNA2,CDC25A,CDC6,CDK1,CDKN2A,CEBPD,CEBPE,CHEK1,CSDA,E2F1,EAPP,FHL2,GAB2,GAS2L1,HIST1H2AG,HIST1H2BJ,HIST2H4A,JMY,MAD2L1,MAD2L1,MDM4,MFAP1,MLH1,MSH2,MSH2,MT1G,MYBL2,MYC,NCOA3,PPP1R13B,PPP1R13B,PRR11,RAD51,RAD54L,RB1,RB1,RB1,RB1,RB1,RB1,RBL1,RBL2,RECQL,TFDP1,TP53BP2,TP53BP2,TP53INP1,TTK,TYMS,UXT,ARID3A,ATM,ATR,BRCA1,BRD2,CCNA1,CCNA2,CDK1,CDK3,CDK7,CDKN2A,CEBPE,CHEK2,CREBBP,CTDP1,CUL1,DDB2,E2F6,GTF2H1,KAT5,MDM4,MNAT1,NCOA3,NCOA6,NDN,NFKB1,NPDC1,PARP1,PHB,PURA,RB1,SERTAD2,SKP2,SP1,SP2,SP3,SP4,TFDP1,TFDP2,TOPBP1,TP53,TP53BP1,TRRAP,ARID3A,BRD2,CCNA1,CCNA2,CDK2,CDK7,CDT1,CREBBP,CUL1,DNMT1,FHL2,GSK3B,GTF2H1,HDAC1,MDM4,MGA,MYBL2,NCOA6,NDN,NDNL2,NFKB1,NPDC1,Nfkb1,PHB,PKIB,PURA,RB1,RBBP4,RBL1,RING1,RNF144A,SKP2,SP1,SP2,SP3,SP4,SPIB,Sp1,TEAD3,TFDP1,TFDP2,TOPBP1,TP53BP1,TRRAP,UBC
Protein Size: 437 - 分子量
- 47 kDa
- 基因ID
- 1869
- NCBI登录号
- NM_005225, NP_005216
- UniProt
- Q01094
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