Dual Specificity Phosphatase 4 (DUSP4) (C-Term) Peptide
DUSP4
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all DUSP4 products
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- GQLLQFESQV LATSCAAEAA SPSGPLRERG KTPATPTSQF VFSFPVSVGV
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-DUSP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
- 别名
- zgc:55423 Peptide, DUSP4 Peptide, typ Peptide, hvh2 Peptide, mkp2 Peptide, mkp-2 Peptide, MGC131045 Peptide, HVH2 Peptide, MKP-2 Peptide, MKP2 Peptide, TYP Peptide, 2700078F24Rik Peptide, AI844617 Peptide, BB104621 Peptide, E130306H24Rik Peptide, Mkp-2 Peptide, Mkp2 Peptide, dual specificity phosphatase 4 Peptide, dual specificity phosphatase 4 S homeolog Peptide, dusp4 Peptide, DUSP4 Peptide, dusp4.S Peptide, Dusp4 Peptide
- 背景
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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
Alias Symbols: HVH2, MKP-2, MKP2, TYP
Protein Interaction Partner: GRIN1,GRIN2D,MAPK1,MAPK14,MAPK3,MAPK8,MAPK9,CRMP1,MAPK14,MAPK3,MAPK8,Mapk14
Protein Size: 394 - 分子量
- 43 kDa
- 基因ID
- 1846
- NCBI登录号
- NM_001394, NP_001385
- UniProt
- Q13115
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